I am an inventor and entrepreneur. In 2023, I launched FutureHouse, a new research lab in San Francisco focused on building an AI Scientist.

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Some problems I think are interesting:

• How we can engineer human biology, including how we can design interventions to repair and improve our bodies, how we can deliver those interventions to where we want them to go, how we control them once they are in the body.

• How we can increase the rate at which we iterate on new therapies by a factor of 10.

• How we can interface with the brain and with the immune system. I gave a TED talk about accessing the brain.

• How we can create new kinds of life.

• How we can regenerate limbs and other body parts.

• How we can put humans into hibernation.

• How we can accelerate science using machine learning.

• How we can measure which things in the world are conscious and which are not conscious.

• How we can achieve any of the above within my lifetime.

 

I previously ran the Applied Biotechnology Lab at the Francis Crick Institute. Before that, I did my PhD at MIT. I am also interested in metascience, i.e., how we can create new institutions and organizations to facilitate scientific research. I proposed the Focused Research Organization model, which is now being used by a number of philanthropic funders and governments to facilitate scientific moonshots.

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Contact: sam at futurehouse.org